Hybridization profiles of the mammary microarray database
(Under construction - use 'Startup DBs (databases)' to start MAExplorer)
There are hyperlinks from this list to some of MGAP pages which provides
information on the models. Not all of these hybridizations
are currently available in the MAExplorer database at this time.
Note, in the future there will be information on many hundreds of
hybridizations in the database.
The array: cDNA clones spotted on this array are from a
normalized cDNA library from mammary tissue of a day 1 lactating
C57/B6 mouse (I.M.A.G.E. library 103) and from a clone collection from
the Hennighausen lab (full list of clones).
Hybridizations: Hybridizations were been performed with 33P
labeled cDNA prepared from total RNA from mammary tissue and mammary
tumors of wild-type and genetically engineered mice. The following
probes have been used.
- 1. Mammary Development (C57/B6 strain)
- 1.1 virgin (4 weeks)
- 1.2 virgin (6 weeks)
- 1.3 virgin (10 weeks)
- 1.4 pregnancy day 11
- 1.5 pregnancy day 13
- 1.6 pregnancy day 16
- 1.7 pregnancy day 18
- 1.8 lactation day 1
- 1.9 lactation day 10
- 1.10 involution day 1
- 1.11 involution day 2
- 1.12 involution day 4
- 1.13 involution day 7
- 2. Developmental models
- 2.1 Stat5a-null mice
- 2.1.1 pregnancy day 13
- 2.1.2 post-partum day 1
- 2.2 C/EBPbeta-null mice
- 2.3 inhibin betaB-null mice
- 2.4 Rb-null mice
- 2.5 prolactin receptor null mice
- 3. Tumor models
- 3.1
WAP-TAG mice
- 3.1.1 pregnancy day 18
- 3.1.2 post-partum day 1
- 3.1.2 hyperplasia
- 3.1.3 tumor
- 3.2 BRCA1-null mice
- 3.2.1 pregnany day 18
- 3.2.2 lactation day 1
- 3.2.3 tumor 1
- 3.2.4 tumor 2
- 3.2.5 tumor 3
- 3.3.
WAP-int3 mice
- 3.4.
WAP-TGFalpha mice

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Revised: $Date: 2000/01/22 12:45:17 $